Overview of the laboratory infrastructure
SEON has a variety of state-of-the-art and high-quality measuring instruments at its disposal to characterize a wide range of particles in detail with regard to their chemical, physical and biological properties. We offer our cooperation partners and external customers to perform corresponding analyses.
You are welcome to contact us in this regard
On this page you will find a selection of our general laboratory infrastructure:
Siemens Artis Zee Floor, Siemens MagDrug Magnet 2, Stäubli TX200 uniVal Drive
Magnet robot and angio CT
Through the BMBF funding "Center of Excellence for Medical Technology") in cooperation with the company Siemens Healthcare and the Department of Neuroradiology of the University Hospital Erlangen, a C-arm supported angiography system (Siemens Artis Zee Floor) was installed in our animal operating room. With the help of this equipment it is possible to visualize the vascular supply of the experimental tumors in 2 and 3 dimensions. This is an important prerequisite for the correct positioning of our electromagnet MagDrug Magnet 2 (Siemens) in the tumor region. To achieve optimal enrichment of drug-loaded particles in the tumor, our magnet was installed in 2019, also through the support of the Manfred Roth Foundation, on a TX200 uniVal Drive robotic arm from Stäubli. With a robot-controlled, freely programmable and positionable magnet, all body regions should be able to be approached and a change of position should also be possible during treatment.
Büchi Minipilot 15
Synthesis reactor
Minipilot 15 system from Büchi for highly scaled syntheses, consisting of a double-walled 15 liter glass reactor temperature-controllable from -60 °C to +200 °C. The reaction chamber is CIP-capable (Cleaning in Place) and the modular design allows the exchange of components to adapt to different synthesis requirements. A dosing unit, a hand hole for reactant addition, an inert gas connection, a stirring shaft feedthrough, a reflux condenser, and a manometer for pressure monitoring are mounted above the cover plate, which was specially designed for particle syntheses. This enables a small-scale parameterization process for synthesis adaptations from laboratory scale to larger-scale production volumes under quality-controlled conditions.
KrosFlo Research IIi
Tangential flow filtration system
The KrosFlo Research IIi from Repligen is suitable for microfiltration and ultrafiltration of both small volumes of 1 ml, but also larger volumes up to 10 L. The system covers overflow rates from 0.01 to 2300 ml/min with one pump head and up to 3800 ml/min with an optional second pump head. This also allows samples to be gently concentrated and purified.
Verasonics Vantage 64 LE
Ultrasonic device
The "Vantage 64 LE" is a research ultrasound device from the company Verasonics. While in medically used systems the raw data is already displayed processed (B-scan, color Doppler, etc.) and it is not so easy to access the raw data, the Vantage system offers the possibility to access the raw data, to program the imaging itself and also to influence the sending and receiving of the ultrasound signal.
Christ Alpha 1-2 LD Plus
Freeze Dryer
Freeze drying is based on the physical process of sublimation: In freeze drying, the ice crystals sublime directly into the gaseous state without the intermediate occurrence of a liquid phase. With the Christ Alpha 1-2 LD Plus, we therefore have a device that is suitable for the gentle drying of high-quality products.
Milli-Q Direct 8
Ultrapure water treatment system
For both synthesis and analysis, it is not possible to take water directly from the tap. Although tap water is drinkable, it still contains numerous "impurities" that interfere with sensitive processes. Therefore, before use, the water is purified by reverse osmosis and a bactericidal UV lamp and then filtered.