Prof. Dr. rer. nat. Dr. habil. med. Stefan Lyer

HNO-Klinik

Professorshop for AI-assissted nanomaterials. Deputy Head of SEON; Head of Oncology and Imaging Unit; Biologist

Sektion für Experimentelle Onkologie und Nanomedizin (SEON)
Glückstraße 10a
91054 Erlangen

Institutions
HNO-Klinik

Phone
+49 9131 85-34769

Fax
+49 9131 85-34828

stefan.lyer(at)uk-erlangen.de

Education, Training and Academic Positions

Curriculum Vitae

Since 07/2022: Professorship for AI-assissted nanomaterials

at the FAU Erlangen-Nuremberg

01/2021: Teaching authorization

in the subject "Experimental Medicine

12/2020: Habilitation

at the medical faculty of the Friedrich-Alexander-University Erlangen-Nuremberg

Topic: "Preclinical animal models and imaging in nanomedicine"

Since 2011: Deputy Head

of the Section of Experimental Oncology and Nanomedicine (SEON) of the ENT Clinic, Head and Neck Surgery at the Universitätsklinikum Erlangen

Since 05/2008: Research associate

at the Section of Experimental Oncology and Nanomedicine (SEON) of the ENT Clinic, Head and Neck Surgery at the Universitätsklinikum

2006-2008: Research associate

in the Department of Molecular Genome Analysis at the German Cancer Research Center (DKFZ) in Heidelberg

2001-2006: PhD Student

at the German Cancer Research Center Heidelberg, Dept. of Molecular Genome Analysis

Topic: "Investigation of the role of DMBT1 in non-small cell lung cancer"

1995-2001: Biology diploma program

at the Friedrich-Alexander-University Erlangen-Nuremberg (Major: Microbiology, Minors: Biochemistry, Zoology, Medical Physics and Biophysics)

Diploma thesis at the Department of Microbiology (Prof. Dr. W. Hillen): "Characterization of the response regulator DegU from Bacillus subtilis: secondary structure and interactions with DNA regions of a potential target gene"

Scientific and educational activities

Educational activity

Lecturer: FelasaB course at the Franz Penzoldt Center
Lecturer: Lecture "Metallic Nanoparticles in Medicine" at the Faculty of Science of FAU, organized by Prof. Kryschi
Lecturer: Seminar series "Preparation for scientific work for physicians in the 2nd semester", at the medical faculty of FAU Erlangen/Nuremberg, organized by Prof. Schiebel
Lecturer: Lecture "Biomedical Applications in Nanomedicine and Nanotoxicology" at the Faculty of Natural Sciences of FAU/Nuremberg
Supervision of seminar, bachelor and master theses of the Natural Science and Technical Faculty of the FAU Erlangen/Nuremberg.
Supervision of PhD projects from the Medical and Technical Faculty of the FAU Erlangen/Nuremberg

Scientific activity
General: Development and in vitro/in vivo application of superparamagnetic iron oxide nanoparticles (SPIONs) for medical applications in imaging, oncology, atherosclerosis and infectious diseases

Projects:

Magnetic drug targeting in oncology.
Magnetic Drug Targeting in Arteriosclerosis
Integration of robotics into treatment procedures for magnetic drug targeting in the treatment of tumors and arteriosclerosis
Development of flow phantoms for the study of physical parameters in Magnetic Drug Targeting in preparation for the use of self-learning algorithms.
Alignment of simulations and experiments/flow tests for Magnetic Drug Targeting.
Combination of magnetic drug targeting and magnetic hyperthermia (DFG proposal submitted).
Magnetic resonance imaging in the field of oncology and arteriosclerosis
Imaging of liver tumors in MRI (funded by: Manfred Roth Foundation)
Ultrasound imaging of nanoparticles (DFG funding)
Comparison of imaging properties/biocompatibility of different commercial nanoparticles and SEON nanoparticles (funded by: Else Kröner-Freseniusstiftung)
Generation of cell lines in the field of ENT oncology
Sepsis diagnostics - and treatment (funded by: Dr. Robert-Pfleger Stiftung)
Method transfer for the approval of nanoparticles
In vitro diagnostics of diseases, e.g. SarsCov2 antibody status